Subrata P. Profile

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$10 USD / hour

bangalore,

india

$10 USD / hour

It's currently 8:12 AM here

Joined August 22, 2014

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Subrata P.

@subratapandit

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$10 USD / hour

bangalore,

india

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Articles Content Writer - Copywriting Freelancer - Biology Assistant

I am looking forward to being hired by you for all your Academic Writing jobs. I have experienced on academic Writing (scientific and medical) and have a blend of experience in the area of Article Rewriting and so my service will prove to be useful for your projects. I have a distinguished career as a Academic Writer. I am ready to be hired by you and start work today.

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Portfolio

Effect of Coleus forskohlii and its Major Constituents on Cy

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Experience

Olive Lifesciences Pvt Ltd

Apr 2013 - Present

• Project design, Project writing, management, data analysis and report writing • Manuscript preparation and publication in journals • Providing tech support to R & D and Marketing team • Evaluating product safety through drug interaction study by CYP450 induction and inhibition assay • Pharmacological activity of extract and phytomolecules • Process development of natural products including extract enrichment, isolation, purification and characterization • Standardization of herbal extract and formulations through RP-HPLC

Education

PhD

Jadavpur University,

India

2007 - 2012

(5 years)

M.Sc.

Vidyasagar Viswavidyalaya,

India

2004 - 2006

(2 years)

Qualifications

CSIR, Government of India

2011

Full travel grand to attained International symposium on HPTLC, Basel, Switzerland

Jadavpur University

2012

Jadavpur University

2008

Publications

Ethnopharmacological and phytomedical knowledge of Coleus forskohlii: An approach towards its safety and therapeutic value

Orient Pharm Exp Med (Springer)

Coleus forskohlii Briq. (Family: Lamiaceae) is a fleshy perennial aromatic herb with fibrous roots that grows under tropical to temperate areas in India, Burma, Thailand, Nepal, Pakistan, Sri Lanka, East Africa and Brazil. The rootstock of the plant is used in Ayurveda and other systems of medicine for several ailments such as heart and lung conditions, asthma, digestive disorder, insomnia, muscle spasm, convulsion and skin diseases. Extensive literature survey was performed based on distribution, morphol

Quantification of α-asarone in Acorus calamus by validated HPTLC densitometric method

JPC - Journal of Planar Chromatography - Modern TLC (Akademiai Kiado), 24 (6), 541–544

HPTLC fingerprints are used as potential cost-effective, simple, and highly selective tool that can ensure both quality and batchto- batch reproducibility of the products from medicinal plants. α-asarone is an important marker compound in A. calamus. A simple and rapid HPTLC densitometric method for quantification of this compound in the rhizome of the plant has been developed and validated. This method may be useful for development of quality control and marker analysis profile of this medicinal pl

Indian Medicinal Plants with Hypoglycemic Potential in Bioactive Food as Dietary Interventions for Diabetes: Bioactive Foods in Chronic Disease States.

Academic press, (Elsevier). 235-264

Diabetes mellitus (DM) is described as 'Madhumeha'in Sanskrit in the ancient Indian literature dealing with the human health care systems. It is a metabolic disease caused by genetic or environmental factors. This chronic disease is supposed to occur when there is deficient production of insulin from pancreas (type-1 diabetes) or when the body does not respond to the produced insulin (type-2 diabetes). This results in raised uncontrolled blood glucose level. DM is also a maharoga (major disease) becaus

Pueraria tuberosa: A review on its phytochemical and therapeutic potential

Natural Product Research (Taylor & Francis Online) 1, 1-17.

Pueraria tuberosa (Willd.) DC is a perennial herb commonly known as ‘vidarikanda’, distributed throughout south east Asia. The plant’s tuber is widely used in ethanomedicine as well as in traditional systems of medicine, particularly in ayurveda. It has been used in various ayurvedic formulations as restorative tonic, antiaging, spermatogenic and immune booster and has been recommended for the treatment of cardiovascular diseases, hepatosplenomegaly, fertility disorders, menopausal syndrome, sexual debili

Botanicals as medicinal food and their effects on drug metabolizing enzymes.

Food and Chemical Toxicology (Elsevier), 49 (12), 3142-3153.

Botanicals fall under different regulations in different countries and are mostly consumed without the consultation of the healthcare professional. Over the last decade, utilization of herbal therapies has been extensively documented. The findings indicate the possibility of potential herb–drug interactions due to the concomitant administration of herbal extracts and prescription/over-the-counter drugs. Simultaneously, with the increasing public awareness and search for safer herbal remedies, the study on h

Quantification of glycyrrhizin in Glycyrrhiza glabra extract by validated HPTLC densitometry

J. AOAC International (AOAC International). 93(2), 492-495

Glycyrrhiza glabra Linn (Family-Fabaceae) is active as an anti-allergic, anti-inflammatory, spasmolytic, mild laxative, antistress, antidepressive, antiulcer, liver protective, estrogenic, emmenagogue, and antidiabetic substance, and is widely used in the Indian system of medicine. The major bioactive constituent is glycyrrhizin. A simple HPTLC method has been developed to control the quality of raw as well as finished glycyrrhiza using glycyrrhizin as the bioactive marker. The solvent system was optimized

Cytochrome P450 inhibition assay for standardized extract of Terminalia chebula retz.

Phytotherapy Research (Wiley Online Library). 25(1), 2011, 151-154.

The hydroalcoholic extract of fruit pulp of Terminalia chebula Retz. was standardized and evaluated for its safety through cytochrome P450 (CYP 450) inhibition assay. Standardization was performed through high performance thin layer chromatography (HPTLC) using gallic acid (GA) standard. Cytochrome P450-CO complex microplate assay was performed using rat liver microsomes. The effect of standardized extract, its fraction and bioactive marker compound were comparatively evaluated for its effect on CYP P450 en

P450 inhibitory potential of Triphala-A Rasayana from Ayurveda.

Journal of Ethnopharmacology (Elsevier)

Ethnopharmacological relevance: ‘Triphala’ is one of the age-old, most commonly used polyherbal preparation from Ayurveda as Rasayana drug. Aim of the study: This study was aimed at evaluating the effect of ‘Triphala’ on drug modulating enzymes to assess its safety through its potential to interact with co-administered drugs. Materials and methods: The cytochrome P450 inhibitory effect of ‘triphala’ formulation was investigated on rat liver microsomes using CYP450–CO complex assay and on individual isofor

RP-HPLC-DAD for simulataneous estimation of mahanine and mahanambine in Murraya Koenigii

Biomedical Chromatography (Wiley Online Library), 25(9), 959-962

Murraya koenigii leaves (Rutaceae) are widely used as food condiments in various food preparations in India. They possess a wide range of biological activities including antioxidant, antibacterial, anticancer, hypoglycemic and hypolipidemic activity. A rapid reverse-phase high-performance liquid chromatography (RP-HPLC) method has been developed for quantitative estimation of mahanine and mahanimbine, two major bioactive alkaloids in this plant. The amounts of mahanine and mahanimbine were detected as 9.56

Metabolism mediated interaction of α-asarone and Acorus calamus with CYP3A4 and CYP2D

Fitoterapia (Elsevier), 82(3), 369-374

The present study was aimed to investigate the possible interaction of the standardized extract of Acorus calamus (AC)with Cytochrome P450 enzyme, quantitative determination of the α-asarone in the AC rhizomewas performed by RP-HPLC method. In vitro interaction of the plant extract was evaluated by CYP450-carbonmonoxide complex (CYP450-CO) assay. Effect on individual isoforms such asCYP3A4 and CYP2D6isozymeswere analyzed through fluorescence product formation and respective IC50 valueswere determined. CYP45

Exploring the possible metabolism mediated interaction of Glycyrrhiza glabra extract with CYP3A4 and CYP2D6

Phytotherapy Research (Wiley online library), (10):1429-34.

The rhizome of Glycyrrhiza glabra L. (licorice) is used very widely in Indian and Chinese traditional medicine, and it is a popular flavor ingredient of drinks, sweets and candies. Its medicinal uses include treating bronchitis, dry cough, respiratory infections, liver disorders and diabetes. Glycyrrhizin is normally considered to be its biologically active marker, so a rapid RP‐HPLC method was developed for the quantitative estimation of glycyrrhizin in the extract. The effect of the standardized extract

Cytochrome P450 inhibitory potential of selected Indian spices—possible food drug interaction.

Food research International (Elsevier), 45, 69–74.

Spices constitute an important group of food which is virtually indispensable in the culinary art. In a view, these spices feared to pose a probability to affect the disposition of conventional pharmaceuticals through inhibition of human cytochrome P450 (CYPs) enzymes. In the present study an approach has been made to evaluate the possible CYP inhibition potential with some Indian spices (Capsicum annuum, Murraya koenigii, Zingiber officinale) and their major bioactive compounds, in combination with pooled